BioOracle
Evidence-Based Analysis

FDA Approval Likelihood

Real-time probability scores synthesized from ClinicalTrials.gov, OpenFDA adverse event data, and SEC regulatory disclosures.

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Scoring Methodology

Our rules-based engine combines three independent data streams into a single probability score.

Phase Score

Historical FDA approval rates by clinical phase. Phase 1 (8%), Phase 2 (27%), Phase 3 (65%). Adjusted for trial status and completion.

Base + Status Modifier

Safety Score

Comparison of adverse event profile against GLP-1 class baseline from OpenFDA FAERS data. Serious AE elevation is penalized.

-0.30 to +0.05 range

Disclosure Score

NLP sentiment analysis of SEC 10-K, 10-Q, 8-K filings for regulatory language and risk factor changes.

Sentiment Quartiles
ClinicalTrials.gov API v2
OpenFDA FAERS
SEC EDGAR